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A systematic approach to cancer: evolution beyond selection

This recent open access paper in Clinical and Translational Medicine caught my attention primarily because it invokes the concept of stigmergy. It’s unusual, though not surprising, that the idea is now finding some currency in medicine. Eukaryotic cells have an entire panoply of communicative and cooperative mechanisms. Since the individual cellular participants can have independent goals in…

Martini time

Staying true to the spirit of the recipe as handed down by the patron saint of martinis, Luis Buñuel, here is a marriage made in heaven. The London Nº1 is an absolutely superb well-priced not gimmicky new gin on the market: so smooth, it was palatable straight up ice-cold! Where I respectfully deviated from Buñuel was my use of Fee Brothers bitters rather…

The Cultured Life and why it is worth pursuing

Joseph Epstein, still as sharp as a whistle, in The Weekly Standard. JE’s coinage “virtucrat”  (“any man or woman who is certain that his or her political views are not merely correct but deeply, morally righteous in the bargain”) is the precursor to the term “virtue-signaling”, the condition befalling many academics, politicians and in all probability many…

Walker Percy Wednesday 137

I will not try to decide here whether what the word apple conjures up in your mind, its signifié, is a percept or a concept, because it is somewhere in between, A percept refers to an individual apple. A concept is an abstraction from all apples, a definition of apple. But the signifié of apple…